Overview of Department & Mentor
The Heart Institute is comprised of 16 centers and programs to diagnose and treat an array of heart conditions in all types of patients. Led by Dr. Eduardo Marban, the center provides expertise in specialties including transplantation, stem cell therapy, congenital heart disease, women's heart health, valve disorders, arrhythmia, and hypertension. Not only is the Heart Institute committed to caring for patients they are committed to conducting cutting edge research. Due to the extensive research being conducted right here at the Cedars-Sinai Heart Institute patients have access to pioneering research techniques.
Dr. Goldhaber's lab focuses on studying the regulation of cardiac excitation- contraction coupling in health and disease, with a particular focus on the effects of metabolic inhibition, ischemia and heart failure on sodium-calcium exchange. A new focus has been on the genesis of pacemaker activity in the sinus node which has led to an NIH funded project to understand the heart's natural pacemaker activity using laser scanning confocal microscopy, voltage mapping, and single cell electrophysiology using a patch clamping technique.
Dr. Goldhaber was among the first to describe the effects of metabolic oxidative stress on cardiac excitation - contraction coupling and calcium regulation. He was also a leader in the study of sodium-calcium exchange and its effects on excitation-contraction coupling in genetically modified mice.
Role Summary & Objectives
This internship in Dr. Goldhaber's lab will provide an opportunity to explore complex scientific research learning experiences as well as well as potential career opportunities. The internship will consist of intensive hands on training in research on the disease known as Heart Failure with Preserved Ejection Fraction. Dr. Goldhaber's lab uses an animal model of this disease and the studies involves interaction with laboratory animals. The trainee will learn, practice and administer various techniques such as cardiac ultrasound/echocardiography, hemodynamic monitoring (non-invasive and invasive), electrocardiography, and intracardiac electrogram recording with voltage mapping. The protocols will also involve testing the efficacy of cardiac stem cells and exosomes on this model of illness. By the end of the internship the trainee will have an in depth understanding of the basis of these principals and hopefully continue to fulfill their interest in research.
Required Education & Experience
• Must be 18 years of age or older.
• Must have a HS Diploma or GED.
• Must reside in the greater Los Angeles area or surrounding cities while conducting all activities related to the intern or visitor appointment.
• INTERNS: Those participating for academic credit must receive academic credit for the duration of the internship.
Preferred Education & Experience
Basic biology-related, chemistry, physics or math college curriculum with lab exposure in college including advanced lab courses; Prior experience in a basic research laboratory.
Working Title: Research Intern (unpaid)
Business Entity: Heart Institute Operations
Job Category: Students/Interns/Trainees
Position Type: Per Diem
Base Pay:$16.78 - $24.71
Our compensation philosophy
We offer competitive total compensation that includes pay, benefits, and other recognition programs for our employees. The base pay range shown above takes into account the wide range of factors that are considered in making compensation decisions including knowledge/skills; relevant experience and training; education/certifications/licensure; and other business and organizational factors. This base pay range does not include our comprehensive benefits package and any incentive payments that may be applicable to this role. Pay Transparency Non Discrimination Provision (PDF) (opens in new window)
Diversity and Inclusion at Cedars-Sinai
We are caretakers and innovators committed to the pursuit of equitable healthcare. But health equity is not possible without representation. Our commitment to diversity goes beyond demographics or checking boxes. Our people must reflect the diverse identities, experiences and geographies of the communities and patients we serve – because that’s what our patients, colleagues and communities deserve. Quality Care and Research—For All, By All (opens in new window).
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